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Phạm Văn Vĩ, Thái Thị Cẩm, Nguyễn Duy Tuấn(1), Hứa Hữu Bằng, Trần Quang Đệ(2)

KHẢO SÁT TÁC DỤNG CHỐNG OXY HOÁ CỦA CAO CHIẾT THÂN MẬT GẤU NAM

THE SURVEY ANTIOXIDANT EFFECTS OF STEM EXTRACTS FROM BITTER LEAF (Vernonia amygdalina L.)

Tạp chí Phân tích Hóa, Lý và Sinh học

2023

1

188

Bitter leaf is a medicinal plant widely used in folk medicine but little studied for the biological effects. Antioxidant activities of stem extracts include n-hexane; chloroform; ethyl acetate; n-butanol; ethanol; and water, determined by the free radicals reduction ability 2,2-diphenyl-1-picrylhydrazyl (DPPH) method and Fe3+ reduction capacity test. On the DPPH model with the best EC50 values of Ethyl acetate and n-butanol, the EC50 values were 63.73µg/mL and 87.21µg/mL. On the Fe3+ reduction test model with the best EC50 being Ethyl acetate, the EC50 value was 72.02µg/mL. Bitter leaf is a plant with the potential for antioxidant capacity and hepatoprotective bioactivity..

Bitter leaf is a medicinal plant widely used in folk medicine but little studied for the biological effects. Antioxidant activities of stem extracts include n-hexane; chloroform; ethyl acetate; n-butanol; ethanol; and water, determined by the free radicals reduction ability 2,2-diphenyl-1-picrylhydrazyl (DPPH) method and Fe3+ reduction capacity test. On the DPPH model with the best EC50 values of Ethyl acetate and n-butanol, the EC50 values were 63.73µg/mL and 87.21µg/mL. On the Fe3+ reduction test model with the best EC50 being Ethyl acetate, the EC50 value was 72.02µg/mL. Bitter leaf is a plant with the potential for antioxidant capacity and hepatoprotective bioactivity..

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