Our study aims to evaluate clinical features and treatment results of stage I-IIIA non-small cell lung cancer in male patients under 45. Patient and methods: A retrospective descriptive study on 43 male patients under 45 years of age diagnosed with stage I-IIIA non-small cell lung cancer who underwent surgery at K hospital from 1/2018 to 8/2022. Results: The mean age is 37.49 ± 4.5, and the youngest is 27. Most patients had a smoking history: 86%. Chest pain (60.5%) and persistent cough (44.2%) were the most common reasons for admission. Right lung tumors were more common than left lung tumors (74.4%), and peripheral tumors were more common than central tumors (81.4% vs 18.6%). Tumors with a diameter of 3-5 cm are the most common, accounting for 65.1% of all cases. On the CT scanner before surgery, most patients (65.1%) did not have lymph node metastasis. The most common histopathological type is adenocarcinoma (83.6%). The rate of safe surgery without complications was high at 89.4%. The most common complication was infection and pneumonia accounted for 7%. The mean time of removal of pleural drain and postoperative period was 5.60 ± 1.7 days and 11.65 ± 4.5 days, respectively. Conclusion: Non-small cell lung cancer in male patients under 45 has distinct clinical characteristics. The most common surgical method is lung lobectomy with lymph node dissection, which has a low complication rate. More studies are needed to evaluate overall survival, as well as to compare with other groups of patients.