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Khoa học tự nhiên

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Nguyen Hoang Ninh, Dang Xuan Nhat Sang, Duong Manh Hieu, Nguyen Thi Thanh Chi, Nguyễn Thị Thanh Chi(1)

ANTI-MICROBIAL ACTIVITY OF SOME Pt(II) COMPLEXES BEARING 8-OXYQUINOLINE (8-OQ) AND EUGENOL DERIVATIVE AND 3D-STRUCTURE OF COMPLEX [PtCl(8-OQ)(EUGENOL)]

ANTI-MICROBIAL ACTIVITY OF SOME Pt(II) COMPLEXES BEARING 8-OXYQUINOLINE (8-OQ) AND EUGENOL DERIVATIVE AND 3D-STRUCTURE OF COMPLEX [PtCl(8-OQ)(EUGENOL)]

Tạp chí Khoa học - Trường Đại học Sư phạm Hà Nội: Khoa học Tự nhiên

2024

69

118

Four complexes including [PtCl(8-OQ)](arylolefin)] (arylolefin: Eug, M1;Aceug, M2, Eteug, M3, Preug, M4) were obtained by the reaction between8-hydroxyquinoline and K[PtCl3(arylolefin)] in high yields. The 3D structure of M1has been determined for the first time by DFT calculation combined with theexperimental NOESY spectrum. The result showed that M1 exists as distortedsquare-planar coordination with angles of O-Pt-Cl and N-Pt-O of 176.4o and 81.0orespectively. In which 8-OQ coordinates with Pt(II) through both the N and O atoms,Eug bonds with Pt(II) via the C=Cally and in trans position to the N atom of 8-OQ.The investigation of the biological activities of the synthesized complexes showedthat they display weak anti-bacterial and antifungal activities.

Four complexes including [PtCl(8-OQ)](arylolefin)] (arylolefin: Eug, M1;Aceug, M2, Eteug, M3, Preug, M4) were obtained by the reaction between8-hydroxyquinoline and K[PtCl3(arylolefin)] in high yields. The 3D structure of M1has been determined for the first time by DFT calculation combined with theexperimental NOESY spectrum. The result showed that M1 exists as distortedsquare-planar coordination with angles of O-Pt-Cl and N-Pt-O of 176.4o and 81.0orespectively. In which 8-OQ coordinates with Pt(II) through both the N and O atoms,Eug bonds with Pt(II) via the C=Cally and in trans position to the N atom of 8-OQ.The investigation of the biological activities of the synthesized complexes showedthat they display weak anti-bacterial and antifungal activities.

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