Nghiên cứu Fibrotest và Fibroscan cho đánh giá không xâm lấn của bệnh xơ gan

Chỉ số đề mục

76.29.34

Lĩnh vực nghiên cứu

Y học lâm sàng

Dạng tài liệu

Tác giả

Lư Quốc Hùng, Trần Việt Tú, Nguyễn Khoa Hiền⁽¹⁾

Nhan đề

Nghiên cứu Fibrotest và Fibroscan cho đánh giá không xâm lấn của bệnh xơ gan

Nhan đề tiếng anh

Studying in ELF, fibrotest and fibroscan for the non-invasive assessment of liver fibrosis

Nguồn trích

Y học Việt Nam

Năm xuất bản

2014

Số

2

Trang

103-106

ISSN

1859-1868

Từ khóa

Fibrotest, Fibroscan, Xơ gan, Chẩn đoán, Điều trị, Kỹ thuật không xâm lấn

Từ khóa tiếng anh

Tóm tắt

Tóm tắt tiếng anh

Methods: In the present study, the test was analyzed retrospectively in patients with chronic liver disease, who received Fibroscan and the FibroTest was classified according to METAVIR and the Ludwig's classification (F0-F4) for patients with chronic hepatitis C and B virus (HCV, HBV) infection and cirrhosis. Results: 46 patients were analysed: 19 with HCV, 3 with HBV, and 24 with cirrhosis. The accuracy (AU ROC) for the diagnosis of significant fibrosis (F or = 2) for Fibroscan and FibroTest was 0.78 (95 percent CI: 0.67 0.89) and 0.69 (95 percent CI: 0.57 - 0.82), (difference not statistically significant). The AUROC for the diagnosis of liver cirrhosis was 0.92 (95 percent CI: 0.83 - 1,00), and 0.91 (95 percent Q:0.83 - 0.99). For 46 patients with reliable Fibroscan measurements the AUROC for the diagnosis of significant fibrosis (cirrhosis) for Fibroscan and Fibrotest were 0.76 (0.92), and 0.67 (0.91). Condusion: Rbroscan and Frotest can be performed with comparable diagnostic accuracy for the non-invasive staging of liver fibrosis. Serum tests are informative in a higher proportion of patients than Fibroscan.

Kí hiệu kho

TTKHCNQG, CVv 46

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