The aim of this research is to determine the changes of blood glucose level, insulin concentration and amylase activity on 30 pigs aft.er pancreatic transplantation. Pigs were transplanted with total pancreatic allograph. Bloods for biochemical test were obtained before and after surgery at the time 3, 24, 48, 72 and 96 hours. Results: Blood glucose level before surgery was 4.93 +/- 2.9 mmollL, after surgery at the time 3, 24, 48, 72, 96h, these parameters were respectively 8.1 +/- 5.5; 4.97 +/- 2.8; 4.96 +/- 2.2; 5.1 +/- 2.1; 4.9 +/- 2.0 mmol/L. Blood insulin level before surgery was 4.0 +/- 2.6 ul/U/mL, after surgery at the time 3, 24, 48, 72, 96h, these parameters were respectively 5.5 +/- 2.2; 3.6 +/- 2.4; 3.1 +/- 2.0; 2.9 +/- 1.7; 2.3 +/- 1.1 ul/U/mL. Blood amylase activity before surgery was 1,295 +/- 496 U/L, after surgery at the time 3, 24, 48, 72, 96h, these parameters were respectively 1,569 +/- 923; 1,365 +/- 504; 1,442 +/- 575; 1,394 +/- 574; 1558 +/- 502 U/L. Conclusion: In the pigs transplanted with total pancreatic allograph blood glucose level and amylase activity increased highly at 3h after surgery then gradually decreased but always higher than that before transplantation while blood insulin level increased at the 3h after transplantation (p 0.05). The next time after transplantation, blood insulin levels tend to decrease gradually lower than these levels before transplantation.
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