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Lê Ngọc Tú, Trần Đại Lâm, Đỗ Phúc Quân, Nguyễn Vân Anh, Lê Trọng Huyền, Cao Hồng Hà(1)

TỔNG HỢP VẬT LIỆU NANOCOMPOZIT TRÊN CƠ SỞ GRAPHEN OXIT KHỬ, POLYDOPAMIN VÀ HẠT NANO ĐỒNG CHO CHẾ TẠO CẢM BIẾN XÁC ĐỊNH SULFAMETHOXAZOLE

SYNTHESIS OF NANOCOMPOSITE BASED ON REDUCED GRAPHEN OXIDE, POLYDOPAMINE AND COPPER NANO PARTICLES FOR SENSORS OF SULFAMETHOXAZOLE

Tạp chí Phân tích Hóa, Lý và Sinh học

2023

2

39

Development of an effective electrochemical sensor for the sensitive detection of antibiotics in food, pharmaceutical formulations and biological liquids is of current interest. We have looked at possibility of rapid detecting sulfamethoxazole (SMZ), an antibiotic of the sulfonamide family, using a composite of reduced graphene oxide, polydopamine and copper nanoparticles as a modified electrode. The important parameters for synthesis of the composite were identified. Using the modified sensor, linear range of SMZ concentration is 4 - 80 μM, with R2 = 0,9893 and LOD of 1.12 M. Furthermore, the modified electrodes were used for the examination of the SMZ content in a commercial product, with reasonable recover

Development of an effective electrochemical sensor for the sensitive detection of antibiotics in food, pharmaceutical formulations and biological liquids is of current interest. We have looked at possibility of rapid detecting sulfamethoxazole (SMZ), an antibiotic of the sulfonamide family, using a composite of reduced graphene oxide, polydopamine and copper nanoparticles as a modified electrode. The important parameters for synthesis of the composite were identified. Using the modified sensor, linear range of SMZ concentration is 4 - 80 μM, with R2 = 0,9893 and LOD of 1.12 M. Furthermore, the modified electrodes were used for the examination of the SMZ content in a commercial product, with reasonable recover