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  • Công bố khoa học và công nghệ Việt Nam

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Y học lâm sàng

Vũ Hồng Thăng, Vương Quang Phước(1)

Sự đáp ứng của Pegylated Liposomal Doxoruncin trong ung thư buồng trứng tái phát, di căn

Response of lipodox (pegylated liposomal doxorubicin) in recurrent ovarian carcinoma

Y học Việt Nam

2015

2

23-27

1859-1868

Aims: Evaluate the response of Lipodox (pegylated liposomal doxorubicin) in patients with recurrencefmetastastic ovarian carcinoma in K hospital. Results: Completed response was 15.4 percent Single substance and 34.6 percent met one part, the clinical benefit achieved 63.5 percent. The tumor pelvic peritoneum-drive had more response as compared to liver metastasis, lungs and lymph nodes. The response rate was 50.0 percent for single and 57.1 percent of 2 tumors and more. The response rate depended on the previous chemotherpay and metastatic status. Cystadenoma may have the highest response rate of 54.8 percent. Index CA-125 in blood after treatment decreases corresponding response on tumor entity. Conclusion: Monochemotherapy Lipodox is effective in patients with recurrent ovarian carcinoma after platinum treatment.

TTKHCNQG, CVv 46