This study is to assess the impact of the COVID-19 pandemic on the Vietnamese stock market’s industries from March 2020 to March 2021. The study finds out the short-term and long term effects of macro factors such as exchange rate, oil price, and gold price, and variables representing the COVID-19 pandemic’s developments such as the number of new COVID-19 cases, recoveries and deaths on Vietnam's stock market. Based on the study’s results, some policy recommendations are made to help the authorities promptly control and protect Vietnam's stock market from unusually volatile events such as the COVID-19 pandemic, and help investors identify the volatility trend of the stock market to make appropriate investment decisions.