This study was conducted by interviewing 40 households with and without access to waste collection services of communities in rural areas (Vinh Thanh district) and central areas (Cai Rang district) of Can Tho City. The purpose of the study is to evaluate the consumption, management, and impact of plastic waste on public awareness. Research results showed that the forms of consumption of plastic products are very diverse despite knowing they can be harmful to health. In addition, people recycle/reuse plastic waste as a measure of waste and plastic waste management in the community because they do not have access to waste collection services. For communities with access to waste collection services, waste is often not segregated and the reuse of plastic is not systematic. In particular, people are aware of the harmful effects of plastic and the trend of using natural materials in daily life is becoming popular. However, plastic reduction and waste management have not been uniformly implemented due to the different characteristics of population groups, service accessibility as well as high cost of collection services.