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  • Công bố khoa học và công nghệ Việt Nam

76.29.37; 76.29.49

Y học lâm sàng

Lê Công Định(1), Vũ Công Lương

Nghiên cứu đặc điểm lâm sàng, cận lâm sàng và đánh giá kết quả phẫu thuật cắt u tuyến cận giáp tại khoa Tai Mũi Họng bệnh viện Bạch Mai

Study on clinical and para-clinical characteristics, and evaluation of surgical results of parathyroid tumors in Otorhinolaryngology Department of Bach Mai Hospital

Tai Mũi Họng Việt Nam

2012

3

21-27

1859-3704

Parathyroid adenoma is a rare disease, mostly benign. The diagnosis is often confused or missed due to variabe clinical manifestations in different specialties. The standard treatment is surgical remove. Objective: study the clinical manifestations, laboratory findings and surgical treatment outcome. Methods: 20 patients suffering from parathyroid adenoma treated with surgical removal. Descriptive retrospective study. Results: average age 47.8. The clinical manifestations are mainly renal signs, bone and non-specific signs like fatigue, weight loss, polydipsia... All have hypercalcemia, elevate PTH The sensivity of ultrasound and Tc 99m sestamibi scan can localize the tumor in 70-80 percent. Frozen section helps to confirm the tumor removed. All patients have a decrease more than 50 percent intraoperative PTH 10 minutes after tumor extirpation. PTH level is normal after 24 hours and Calcemia returns normal after 3 days. Conclusion: the manifestations of the parathyroid adenoma is very variable with non-specific signs. Diagnosis is based on hypercalcemia and elevated PTH Scintigraphy is an useful tool, high sensivity, specificity. Minimally invasive parathyroidectomy assure successful outcome.

TTKHCNQG, CVv348