FLAVONOID VÀ TRITERPENOID TỪ PHẦN TRÊN MẶT ĐẤT LOÀI BƯỚM BẠC SÀI GÒN MUSSAENDA SAIGONENSIS

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Tác giả

Phan Nhật Minh, Nguyễn Tấn Phát, Nguyễn Diệp Xuân Kỹ⁽¹⁾, Trần Huy Khiêm, Lê Văn Dũng, Đặng Chí Hiền, Trần Duy Khang, Mai Đình Trị

Nhan đề

FLAVONOID VÀ TRITERPENOID TỪ PHẦN TRÊN MẶT ĐẤT LOÀI BƯỚM BẠC SÀI GÒN MUSSAENDA SAIGONENSIS

Nhan đề tiếng anh

FLAVONOID AND TRITERPENOID COMPOUNDS FROM THE AERIAL PARTS OF MUSSAENDA SAIGONENSIS

Nguồn trích

Tạp chí Phân tích Hóa, Lý và Sinh học

Năm xuất bản

2023

Số

4

Trang

20

ISSN

Từ khóa

Từ khóa tiếng anh

Tóm tắt

Phytochemical investigation of the aerial parts of Mussaenda saigonensis led to the isolation of 6 compounds, including 3,5,6,7,8,3′,4′-heptamethoxyflavone (1), nobiletin (2), quercetin (3), -amyrin (4),oleanolic acid (5) và maslinic acid (6). The chemical structures of the substances were determined by the analysis of spectroscopic data and by comparing them with existing literature. All the individual substances were documented for the first time from Mussaenda saigonensis, to the best of our understanding. The isolated compounds were assessed for their ability to prevent the formation of nitric oxide (NO). Compounds 3, 5 showed NO inhibition with the IC50 values ranging from 34.57, to 35.55 µM while other compounds were weak or inactive compared to the positive control L-NMMA (IC50 29.32 μM).

Tóm tắt tiếng anh

Phytochemical investigation of the aerial parts of Mussaenda saigonensis led to the isolation of 6 compounds, including 3,5,6,7,8,3′,4′-heptamethoxyflavone (1), nobiletin (2), quercetin (3), -amyrin (4),oleanolic acid (5) và maslinic acid (6). The chemical structures of the substances were determined by the analysis of spectroscopic data and by comparing them with existing literature. All the individual substances were documented for the first time from Mussaenda saigonensis, to the best of our understanding. The isolated compounds were assessed for their ability to prevent the formation of nitric oxide (NO). Compounds 3, 5 showed NO inhibition with the IC50 values ranging from 34.57, to 35.55 µM while other compounds were weak or inactive compared to the positive control L-NMMA (IC50 29.32 μM).

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