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Nguyễn Thị Thanh Tú, Đỗ Thị Phương, Nguyễn Trần Thị Giáng Hương, Phạm Thị Vân Anh(1), Nguyễn Thị Ngọc Lan

Tác dụng giảm đau, chống viêm của viên nang hoàng kinh trên động vật thực nghiệm

The anti-inflammatory and pain reliever effect of Hoang kinh capsule in white mice experimental models

Nghiên cứu y học

2014

5

43-50

0868-202X

The purpose of this study is to evaluate the pain reliever and anti-inflammatory effectiveness of Hoang kinh capsule. Experimented was conducted on white mice; pain wa~ induced using heat and measured by the tail flick model indicated that Hoang kinh capsule has .not reduced pain at the doses of 9.6 g/kg and 28.8 g/kg body weight. Hoang kinh capsule has reduced pain induced by acetic acid in mice at two doses, 9.6 g/kg and 28.8 g/kg body weight respectively. Hoang kinh capsule at dose 5.6 g/kg was effective in reducing acute inflammatory after 6 hours on white rat paw edema caused by carragenin. The effectiveness of Hoang kinh capsule at 9.6 g/kg and 28.8 g/kg dosage in preventing chronic anti-inflammatory were comparable to treatment with methylprednisolone at 10 mg/kg by carrageenin - induced model of peritoneal inflammation in rat.

TTKHCNQG, CVv 251