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  • Công bố khoa học và công nghệ Việt Nam

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Trần Danh Cường(1), Cấn Bá Quát, Bùi Hải Nam

Tìm hiểu mối liên quan giữa bất thường nhiễm sắc thể với tăng khoảng sáng sau gáy ở thai nhi

Research on the relation between chromsomal disorder and increase nuchal translucency fetal

TC Khoa học và Công nghệ Thái Nguyên

2012

4

3-6

1859-2171

Nuchal translucency (NT) is the amount of fluid behind fetus's neck. NT is a physiological feature of the fetus and can be measured from 11-14 week of gestation age. NT play an important part in screening chromosomal disorders. Increase of NT between 11 to 14 week is considered a suggestive signs of chromosomal disorders of the fetus. Objectives: to evaluate the rate of chromosomal disorder of the fetuses with increase of NT. Materials and methods: we measured NT of 250 pregnant women in 11-14 week of gestation. Above 3.0 mm considered not normal. Results: the rate of chromosomal disorder is 32.4 percent in those cases of increase of NT among those trisomy 21 is 12.4 percent, monosomy X is 12 percent, trisomy 18 is 5.6 percent, trisomy 13 is 0.8 percent and stutural disorder is 1.6 percent. With the range from 3.0 to 3.9 mm, the rate of chromosomal disorder is 10.1 percent, 4.0 to 4.9 mm is 29 percent, 5.0 to 5.9 mm is 48 percent and above 6 mm is 64 percent. Conclusion: increase of NT is a suggestive signs of chromosomal disorder. The thicker NT is, the higher risk of chromosomal disorder.

TTKHCNQG, CTv178