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Ngô Trần Ái Linh, Nguyễn Thị Linh Tuyền(1), Trần Hoàng Lâm, Võ Thị Yến Nhi
Đặc điểm vi khuẩn gây đợt cấp bệnh phổi tắc nghẽn mạn tính tại bệnh viện đa khoa tỉnh Kiên Giang năm 2020
CHARACTERISTICS OF BACTERIOLOGICAL CAUSES OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE AT KIEN GIANG PROVINCE GENERAL HOSPITAL IN 2020
Y Dược học Cần Thơ
2021
43
81-87
Therefore, microbiological assessment to help choose the right antibiotic in the treatment of this disease is very important and has clinical significance. Objectives: 1. Describe the characteristics of pathogenic bacteria causing acute exacerbations of COPD at Kien Giang province General Hospital in 2020. 2. Investigate some related factors to infection with some common bacterial strains causing exacerbations of chronic obstructive pulmonary disease. Materials and methods: A crosssectional descriptive study was conducted on 400 medical records of COPD exacerbations were admitted to hospital for treatment at the Department of Respiratory Internal Medicine at Kien Giang General Hospital in 2020. Data processing method is using SPSS software. Results: COPD exacerbations caused by Gram-negative bacteria account for the majority (79.71%). Some common strains are Klebsiella ssp. (27.54%), Pseudomonas ssp. (20.29%) and Acinetobacter baumannii (17.39%). Klebsiella ssp. are highly resistant to cephalosporin, Pseudomonas ssp. are highly resistant to gentamycin and carbapenems; Acinetobacter baumannii are resistant to ciprofloxacin and cephalosporins. Gram-positive bacteria account for 20.29%. The most common strain is Streptococcus pneumonia (11.59%).They are highly resistant to betalactam. Some factors related to the risk of infection is not smoking reduces the risk of infection with Klebsiella spp. (OR = 0.02, p = 0.016). The risk of infection with Pseudomonas spp. is reduced in the absence of hypertension (OR = 0.067, p = 0.040), type 2 diabetes (OR = 0.11, p = 0.011), old pulmonary tuberculosis (OR = 0.11, p = 0.003). Conclusion: The majority of pathogenic bacteria are gram-negative. Common strains are Klebsiella ssp., Pseudomonas ssp., Streptococcus ssp., Acinetobacter baumannii. Some factors related to the risk of infection such as smoking, having old tuberculosis, having hypertension, having type 2 diabetes.
TTKHCNQG,, CVv 482
