The aim of this study was to isolate bacterial strains that are capable of degrading protein and cellulose from different organic domestic waste resources. Effects of isolated bacteria on the survival of earthworms (Perionyx excavates) were also investigated under in vitro study. Seventy five organic waste samples were collected from bazaars, small restaurants and house-hold samples for isolating and screening their functions of protease, cellulase and earthworm survival. The results showed that 58 bacterial strains were isolated from domestic organic wastes. Among them, 46 bacterial isolates released protease activity and 12 bacterial isolates had cellulolytic activity. A quantitative evaluation of these functional bacterial isolates further selected three protein bacterial isolates of pAT3, pPT1, pTVC3 and three cellulolytic isolates of cAT1, cAT1 and cCR1 that had fast degradation of pork and fish meat wastes and vegetable waste samples, respectively. Based on the 16S rRNA sequence, 5 bacterial strains were identified at the species level and one unidentified bacterium. These 6 bacterial strains caused less odour of the organic matter than that of the control treatment and they did not affected on the survival and the growth of earthworms under invitro study.