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  • Công bố khoa học và công nghệ Việt Nam

76.35.45

Y học cơ sở

Đào Văn Tùng, Trần Hoài Nam, Đặng Đức Nhu, Phạm Thiện Ngọc(1), Teruhiko Kido, Seijiro Honme

Nồng độ hormon Steroid ở người mẹ cho con bú sống tại vùng phơi nhiễm Dioxin Việt Nam

To assess the quantitative steroid hormone level and confirm the correlation between salivary steroids and serum hormone in lactating mothers in dioxin hot-spot areas of Vietnam

Y học Việt Nam

2013

0

123-127

1859-1868

Background: Dioxins are knowed as risk factor of various kinds of adverse effects health including cardiovascular disease, diabetes mellitus, cancer. The hormone levels are also known to alter by low dose-exposure to dioxins. Purpose: To assess the quantitative steroid hormone level and confirm the correlation between salivary steroids and serum hormone in lactating mothers in dioxin hot-spot area. Subjects and methods: This study has to carry out on 111 lactatating mothers in Phu Cat airbase - one of three dioxin hot-spots area in Viet Nam with using the control group. Results: Cortisol and cortisone levels in serum and also saliva in dioxin hot-spot are higher than those in non-exposed area (p0.0l); there are the positive correlations (r0,63, p0.001) between steroid hormones concentration in serum and saliva. Conclusion: Salivary cortisol, salivay cortisone levels and also in serum in hot-spot area are higher than those in non-exposed area (p0.01). there are the positive correlations (r0,63, p0,001) between steroid hormones concentration in serum and saliva.

TTKHCNQG, CVv46