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Nguyễn Thị Tú Linh, Vũ Thị Trinh, Lê Lan Phương, Trịnh Hồng Thái, Nguyễn Thị Tú Linh, Trịnh Hồng Thái*, Lê Trung Thọ

Biểu hiện giảm của lncRNA UCA1 trong exosome huyết tương của bệnh nhân ung thư phổi không tế bào nhỏ

Downregulated expression of exosomal long non-coding RNA UCA1 in plasma of patients with non-small cell lung cancer

Tạp chí Khoa học và Công nghệ Việt Nam - B

2024

7B

21

Các phân tử RNA dài không ghi mã (lncRNA) có chủ yếu trong nhân của tế bào và tham gia vào nhiều quá trình điều hoà biểu hiện gen khác nhau. Mức độ biểu hiện bất thường của các phân tử lncRNA được cho là có vai trò đối với hoạt động di căn, xâm lấn và tăng sinh của khối u, trong đó có ung thư phổi không tế bào nhỏ (UTPKTBN)...

Long non-coding RNAs (lncRNAs), mainly found in the nucleus of cells, are involved in different gene expression and regulation processes. Growing evidence has shown that abnormalities in the expression levels of lncRNAs play an important role in tumour metastasis, invasion, and proliferation, especially in non-small cell lung cancer (NSCLC)...

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