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Trương Thị Bình Giang, Đinh Thị Trường Giang(1)

NGHIÊN CỨU XÁC ĐỊNH HÀM LƯỢNG VẾT KIM LOẠI Se, Cu, Zn, Mg, Mn TRONG MÁU CỦA MỘT SỐ BỆNH NHÂN MẮC BỆNH VỀ HÔ HẤP BẰNG PHƯƠNG PHÁP PHỔ KHỐI LƯỢNG PLASMA CAO TẦN CẢM ỨNG (ICP – MS)

STUDY ON DETERMINE THE AMOUNT OF TRACE METALS Se, Cu, Zn, Mg, Mn IN THE BLOOD OF SOME RESPIRATORY PATIENTS BY METHOD OF INDUCTIVELY COUPLED PLASMA – MASS SPECTROMETRY (ICP – MS)

Tạp chí Phân tích Hóa, Lý và Sinh học

2022

3

59

Concentration of selenium (Se), copper (Cu), zinc (Zn), magnesium (Mg), manganese (Mn) in blood of patients with respiratory disease were determined by method of inductively Coupled Plasma - Mass Spectrometry (ICP-MS) after sample digestionin a close container in a microwareoven. The result of Se, Cu, Zn, Mg and Mn (ppm) are in the range of 0.0122 – 2.0865, 0.2329 – 1.5815, 1.9094 – 13.0964, 4.3917 –19.1262 and 0.0430 – 0.5703. The detection limits are 0.3870 (ppt) for Se and 0.003; 0.045; 0.0042; 0.0045 (ppt) for Cu, Zn, Mg, Mn respectively. The relative standard deviation (%RSD) of 10 replicated measurement is less than 6%. The recovery range of element is 50,83% to 108,35%. The accuracy of the result shown in the repeatability and recovery performance is ensured according to AOAC.

Concentration of selenium (Se), copper (Cu), zinc (Zn), magnesium (Mg), manganese (Mn) in blood of patients with respiratory disease were determined by method of inductively Coupled Plasma - Mass Spectrometry (ICP-MS) after sample digestionin a close container in a microwareoven. The result of Se, Cu, Zn, Mg and Mn (ppm) are in the range of 0.0122 – 2.0865, 0.2329 – 1.5815, 1.9094 – 13.0964, 4.3917 –19.1262 and 0.0430 – 0.5703. The detection limits are 0.3870 (ppt) for Se and 0.003; 0.045; 0.0042; 0.0045 (ppt) for Cu, Zn, Mg, Mn respectively. The relative standard deviation (%RSD) of 10 replicated measurement is less than 6%. The recovery range of element is 50,83% to 108,35%. The accuracy of the result shown in the repeatability and recovery performance is ensured according to AOAC.