The United States is the largest open economy in the world with a GDP of $25 trillion in 2022. The FED has a specific organizational structure that includes both public and private characteristics. The FED’s monetary policy with the main goal of addressing employment and macroeconomic stability, but having an impact on all central banks of other countries; Since the Covid-19 pandemic, the FED has used 12 tools simultaneously, issued enforcement decisions through the maximum use of traditional tools, combined with urgent new measures to support capital flows to promote post-pandemic economic recovery. The FED’s monetary policy has had a significant impact on Vietnam’s monetary policy, fiscal policy, and capital markets. The analysis also gives recommendations for interest rate policy, exchange rate policy and synchronous coordination between fiscal policy and monetary policy of Vietnam in the coming time The United States is the largest open economy in the world with a GDP of $25 trillion in 2022. The Fed has a specific organizational structure that includes both public and private characteristics. The FED’s monetary policy with the main goal of addressing employment and macroeconomic stability, but having an impact on all central banks of other countries; Since the Covid-19 pandemic, the FED has used 12 tools simultaneously, issued enforcement decisions through the maximum use of traditional tools, combined with urgent new measures to support capital flows to promote post-pandemic economic recovery. The FED’s monetary policy has had a significant impact on Vietnam’s monetary policy, fiscal policy, and capital markets. The analysis also gives recommendations for interest rate policy, exchange rate policy and synchronous coordination between fiscal policy and monetary policy of Vietnam in the coming time.