To describe the traditional medicine clinical characteristics of smokers in Ward 5, District 10, Ho Chi Minh City. Subjects and methods: A cross-sectional descriptive study from April 2022 to the end of October 2022 on 106 smokers aged 15 years and older living in Ward 5, District 10. Results: The age of smokers was mainly in the group 40 – 59 years old (46%), with the higher percentage of men (95% compared to 5%), most of them are self-employed and other occupations (55% and 12%), civil servants (11%), workers (10%), students (6%), unemployment (6%). Mostly time of smoking are 11-30 years (43%), followed by smoking group 31-50 years (33%), under 10 years (21%), over 50 years smokers (3%). Qi-deficiency constitution (22%), Phlegm-wetness (16%), Yin-deficiency (16%), Blood-stasis (14%), Inherited special constitution (12 Wetness-heat (10%), Qi-depressed (7%), Yang-deficiency (7%), Normality constitution was 7%. The most common clinical symptoms are fatigue, shortness of breath, poor appetite (55%), followed by dry thirst, dry eyes, dry skin (44%); cough, sputum stuck in the throat (52%). Conclusion: Smokers are usually male, 40-59 years old, average BMI, most are self-employed, smoking time is 11-30 years, comorbidities are usually hypertension, dyslipidemia. blood, coronary heart disease. Traditional Chinese Medicine Constitution are mainly Qi-deficiency, Phlegm-wetness, Yin-deficiency, Blood-stasis. The most common symptoms are fatigue, shortness of breath, poor appetite, followed by dry thirst, cough with sputum in the throat.