Study was carried out to study the effects of deoxynivalenol and efficacy of detoxifying additives in ameliorating the toxic effects of deoxynivalenol on growth performance of growing pigs. A total of 640 crossbred pigs (Landrace x Yorkshire x Duroc) 60 days of age were assigned into 8 experimental diets according to a completely randomized design (CRD). Eight experimental diets contained: 0 ppm, 3.4 ppm, 7.7 ppm, 17.7 ppm deoxynivalenol, 0 ppm + detoxifying 0.15 percent, 3.4 ppm + detoxifying 0.15 percent, 7.7 ppm + detoxifying 0.15 percent, 17.7 ppm + detoxifying 0.15 percent, respectively. Deoxynivalenol were produced from Fusarium nivale cultured on maize grain with 590 ppm. The results revealed that body weight gain were respectively 2.8 percent, 8 percent and 14.5 percent reduced when a diet containing 3.4 ppm, 7.7 ppm,; 17.7 ppm of deoxynivalenol was fed compared to a control diet. However, average body weight gain were respectively 2 percent, 5 percent and 11 percent greater when a detoxifying additive was added compared to diets without additive. Feed intake was significantly decreased when level of deoxynivalenol in diet increased. Feed Conversion Ratio (FCR) was highest in the diet containing 17.7 ppm of deoxynivalenol and was 3.28. Feed efficiency were respectively 3.0 percent, 5.1 percent and 10.8 percent higher when a diet containing higher, medium or lower of deoxynivalenol levels compared to a control diet. Whereas, feed conversation ratio in the diets with detoxifying additive was 3.0 percent, 4.1 percent and 4.7 percent, respectively higher than control diet. However, feed conversion ratio in the diets containing 7.7 ppm and 17.7 ppm of DON was reduced 1 percent and 6.7 percent respectively when detoxifying additives was supplemented. So, it should be better if detoxifying is used in feed in order to minimize the harmful effects of DON toxins.
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