Continuous veno-venous hemofiltration (CVVH) in septic shock may induce hemostasis disorders. Objective: To study the activity of coagulation factors and the relationship between altered activity of those factors with the severe level of disease and treatment outcomes in septic shock patients with CVVH. Subjects and Methods: 68 septic shock patients with CVVH at Bach Mai hospital. Prospective study - describe, compare I self-control. Results: The recovery of activated coagulation factors: before filtering, the activity of some the extrinsic factors II, V, VII, X and intrinsic factors IX, XI reduced respectively 42.01 percent, 47.85 percent, 41.08 percent, 56 percent, 53.72 percent, 68.49 percent, after filtration, the activity those factors increased respectively 47.12 percent, 61.44 percent, 51.19 percent, 63.51 percent, 56.57 percent, 80.88 percent. After finished CVVH, the activity of VII in survived patients was 62.34 percent, higher than the mortality group (43.86 percent), the activity of factor VIII of low-risk patients was 153.76 percent, higher than the high-risk group (133.3 percent). Conclusion: There was the recovery of the activity of some coagulation factors in septic shock patients with CVVH.
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