The experiment was conducted in Oabaco Ltd Breeding Pigs Company to evaluate the effect of the antibody addition in forms of Ig-Guard Swine and Focus SW12 preparations wit~ doses of 0.2 percent and 0.05 percent, respectively to the diets of suckling and after weaning piglets. The experiments were repeated three times, suckling piglets (7-21 days old) and after weaning (21-33 days old) in 3 groups: control, treatment 1 and treatment 2 were feeding with the diets respectively: no additional, Ig-Guard Swine additional and Focus SW12 additional. The total piglets in each group were 150 (15 sows per lot) for suckling period and 90 for after weaning periods. The results showed that: effects of the additional IgGuard Swine and Focus SW12 preparations as follows: Increase weaning weights 5.49 and 7.5 percent, respectively, weights at 33 days old 6,14 and 7.79 percent, reduce the incidence of diarrhea from 9.8 to 10.7 percent and from 10.1 to 12.0 percent, reduce FCR 0.25 and 0.21 kg and reduced feed costs 3463 and 2978 VND/kg weight gain, respectively in comparison with no supplementation. Should be supplemented Ig-Swine Guard or Focus SW12 preparations to diets of suckling and after weaning piglets.