In silico screening of alkaloids as potential inhibitors of epidermal growth factor receptor

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Tác giả

Bui Thanh Tung⁽¹⁾*, Nguyen Nhu Son, Nguyen Bao Kim, Nguyen Hai Ha , Pham Thi Kim Dung, Nguyen Thanh Tra

Nhan đề

In silico screening of alkaloids as potential inhibitors of epidermal growth factor receptor

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Nguồn trích

Vietnam Journal of Science, Technology and Engineering - C

Năm xuất bản

2023

Số

3C

Trang

85

ISSN

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Tóm tắt

The epidermal growth factor receptor (EGFR) belongs to the HER/erbB receptor tyrosine kinase (RTK) family, serving as a crucial target for cancer treatment. Anti-EGFR drugs, used as a primary treatment for patients with advanced EGFR gene mutations such as T790M, C797S, and L858R, have shown greater efficacy and safety compared to standard chemotherapy...

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