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76.29.30

Y học lâm sàng

Nguyễn Thúy Nga, Trịnh Thị Quế, Đỗ Doãn Lợi, Phạm Thiện Ngọc, Anh Thi Pham(1)

Nghiên cứu sự liên quan giữa Galectin-3 và một số dấu hiệu sinh học khác ở bệnh nhân suy tim

Study on relations of plasma Galectin-3 with other biomarkers in patients with heart failure

Y học thực hành

2024

1

81-83

1859-1663

Objective: Finding relationship between the concentration of Gal- 3 and some biochemical indicators of heart in patients with heart failure. Method: a cross-sectional descriptive study in 50 normal people and 80 patients with heart failure by Framingham criteria. Plasma Galectin-3 concentration was measured according to the principle of Chemiluminescent Microparticle Immunoassay (CMIA). The concentrations of NT-proBNP, troponin T were measured according to principle of Electro chemiluminescent immunoassay (ECLIA). Result: The concentration of Gal- 3 in heart failure patients was 35.01 +/- 20.61 ng/mL. There is asignificantly correlation between the concentration of Gal-3 and NT-proBNP plasma (r = 0.6; P 0.001). There was not the correlation between plasma Gal-3 level and CK-MB, CK, AST, Troponin T and hs CRP. Conclusion: Gal-3 and NT-proBNP are valuable markers in the diagnosis and prognosis of heart failure.

TTKHCNQG, CVv 57