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  • Công bố khoa học và công nghệ Việt Nam

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Nguyễn Xuân Hùng, Phạm Nguyên Tường, Đặng Thanh, Võ Lâm Phước, Châu Minh Khôi(1)

Nghiên cứu kết quả điều trị ung thư vòm mũi họng bằng hóa xạ trị đồng thời tại Bệnh viện Trung ương Huế

Study on the treatment results of nasopharyngeal carcinoma by using concurent chemoirradiation at Centre Oncology of Hue Central hospital

Tai Mũi Họng Việt Nam

2015

1

37-43

1859-3704

Objective: the authors evaluated the benefits (responses and toxicities) of concurent chemoirradiation in treatement nasopharyngeal carcinoma (NPC). Materials and Methods: 41 patients (prospective) advanced NPC treated at Centre Oncology of Hue Central hospital, between January, 2013 and September, 2014. NPC were treated with by CRT using Cisplatin 30mglm21weekly in 6 weeks, total irradiation dose, (70 Gy, tumor; 50 Gy, nodes). Results: Characteristic: median age 46.41 (range 7-68); male/female 2; palpapble cervical lymh nodes 82.9 percent. VCNT (90.2 percent). Stage III (51.2 percent) and IV (41.5 percent); Complete rate is 85.3 percent; partial response rate 14. 7 percent. Acute toxicities of CRT were as follows: leukopenia (51.2 percent), anemia (14.6 percent). No patient developed moderate to severe mucositis and xerostomia ( or = Grade 3). Conclusions: concurent chemoirradiation is a method to improve locoregional, region node control and increase response rate, however also increasing acute toxicities, but low level and acceptable.

TTKHCNQG, CVv 348