Lao Cai is a province in the Northwest Vietnam with favorable natural and climatic conditions for the planning and development of medicinal plants. Recently, along with the increase in cultivated area, medicinal plants in Lao Cai province are facing the increase of many different pests and diseases, including plant parasitic nematodes. This study analyzed 230 soil samples and roots/tubes of 7 medicinal plants including: Platycodon grandiflorus (Jacq.) A. DC., Cynara cardunculus L., Angelica sinensis (Oliv.) Diels, Salvia miltiorrhiza Bunge, Dipsacus japonicus Miq., Codonopsis pilosula (Franch.) Nannf. and Ligusticum striatum DC., recorded 8 genera of plant parasitic nematode. In which, the genus Pratylenchus is the main plant nematodes group on Dipsacus japonicus and Codonopsis pilosula. The genus Meloidogyne is the main pests on Platycodon grandiflorus, Cynara cardunculus and Salvia miltiorrhiza. On Angelica sinensis and Ligusticum striatum, two main genera were recorded, Pratylenchus and Meloidogyne. The typical symptoms caused by plant parasitic nematodes Meloidogyne and Pratylenchus are yellow leaves, stunted plants, lumpy roots, swelling and necrosis were recored.