To cope with the changes in the business environment, enterprises have continuously adopted initiatives on corporate social responsibility (CSR) as a business strategy. These strategies can improve customer attitudes towards a business, and are used to promote tourist preferences for the hotels' brand. These days, hotels have viewed CSR as an important tool to show responsibility honestly and sustainably to enhance their brand. The study aimed to find out the influence of CSR on tourist attitudes and preferences towards brands' hotels in Vietnam. Stakeholder theory, hierarchical effects model, and social identity theory were applied to this study. To test the research model and hypothesis, the method of linear structural modeling (SEM) is used. Research results show that Hotel CSR related to the environment aspect has the strongest impact on tourists' attitude and brand preference.