Concentrations of eight metals (Cd, As, Cr, Co, Cu, Pb, Zn, Ni) in PM2.5 were examined in a suburban area (Dong Anh) and residential urban area (Thanh Xuan) in Hanoi in winter and spring. The results revealed that higher metals in PM2.5 were observed in winter in Dong Anh, while higher metals in PM2.5 were observed in spring in Thanh Xuan due to the different sources at study area. The concentrations of Cu, Pb, Zn, Cd, Cu and As in PM2.5 in Dong Anh were higher than those in Thanh Xuan due to the heavy vehicle, activities industrial production and craft village, which increases emissions into atmospheric. Concentration of Cd, V, Ni, Pb, Mn and Cr in PM2.5 were lower than the allowable values according to EU and WHO standards. The enrichment factor analysis shows that the emission source EF of these metals were related to human activities (traffic, industry, or craft villages). The health risk assessments suggested that As (HQ = 1.1) and Cd (HQ = 1.0) in Thanh Xuan, and As (HQ = 1.6) and Cd (HQ = 1.8) in Dong Anh had non-carcinogenic risks for adults. The cumulative carcinogenic risk of elements was within the acceptable range for both children and adults at both sites.