The objective of this study was to determine the effects of some factors including food additive supplementation, grinding time, and cooking time on the sensory quality of tilapia grilled chopped fish. Fishes were decapitated, gutted, filleted manually, washed, and mixed with different food additive supplementation (flour, cornstarch, sodium tripolyphosphate, and carrageenan) at a concentration of 2%, then the grinding time (1; 1.5; 2 min) and cooking time (2; 4; 6 min) were evaluated to obtain the good sensory quality of the product. Besides, we determined some microbiological indicators affecting the quality of this product. The results showed that the appropriate additive used to tilapia grilled chopped fish was carrageen with a mixing ratio of 2%, grinding time of 2 minutes, and appropriate cooking time of 4 minutes. The results of the microbiological analysis showed that total aerobic microorganisms were below the allowable threshold, and there were no harmful microorganisms to consumers’ health.