To determine the physical exam and diagnostic testing in patients who suffer f-rom obstructive sleep apnea syndrome aged over 65 years old in Bach mai Hospital. Methods: Forty-five patients who suffer f-rom obstructive sleep apnea syndrome aged more than 65 years old agreed to participate in our study and performed polysomnography, f-rom 9/2020 to 7/2021. Results. The most common nocturnal symptom is loud snoring when sleeping, reach to 92.5%, and waking up many times during the night, reach to 75%. 97.6% of patients had Mallampati grade 3-4 (n=42) with an average apnea index of both sexes of 32.63 (n=45). Of which 73.3% of patients have moderate to severe AHI. Patients with obstructive sleep apnea syndrome have Epworth score > 10 and morning headache symptoms only accounted for 20% (n=40). Conclusion: Subjects over 65 years of age with OSA presented with daytime drowsiness, headache, and low morning irritability. Snoring is the most common nocturnal symptom in patients over 65 years of age with obstructive sleep apnea with moderate to severe AHI.