Sagi Bio, a microbial product of thermophilic strains of Bacillus and Streptomyces, is made by the Institute of Environmental Technology, Vietnam Academy of Science and Technology. It has been listed as the permitted biological products for waste treatment by the Ministry of Natural Resources and Environment of Vietnam. In this study, the solid waste of dairy cows was treated by Sagi Bio at household scale in Moc Chau, Son La. The results of using the model show that: i) The temperature of the compost pile of samples using Sagi Bio microbial products increased rapidly after stabilizing the compost pile and the temperature was maintained for about 3 weeks above 50o C. The finishing time was faster in the compost pile using Sagi Bio (8 weeks) than in the control (11 weeks). Using microbial products Sagi Bio has the effect of reducing the generation of NH3, H2S gas during processing; ii) Supplement of Sagi Bio is better inhibiting pathogenic microorganisms such as Salmonella and E. coli to the composting process of cattle waste treatment, iii) Organic fertilizer obtained from dairy cow waste treatment using Sagi Bio has an organic matter content of over 40%, meeting the standards prescribed in QCVN01: 89/2019/BNNPTNT. The results of this study show that the use of Sagi Bio microbial product is effective in the treatment of household-scale cow waste in Moc Chau, Son La.