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  • Công bố khoa học và công nghệ Việt Nam

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Y học lâm sàng

Vũ Thị Thanh Huyền, Hà Thị Hồng Cẩm, Đặng Thị Ngọc Dung, Nguyễn Danh Huy(1)

Giá trị của chỉ số Albumin/Creatinin nước tiểu trong chẩn đoán biến chứng thận ở bệnh nhân đái tháo đường

Value of urine albumin/creatinin ratio in diagnosis of renal diabetic complication

Y học Việt Nam

2015

1

55-60

1859-1868

Objective: To assess the value of urine albumin/creatinine ratio in diagnosis of kidney complications in type 2 diabetic patients. Subjects and Methods: A descriptive cross-sectional study included 177 typ 2 diabetes, diagnosed according to ADA criteria 2012. Urine ACR were calculated by UX2000 and Cobas 6000. Results: The mean age: 68.8 +/- 8.1, female/male: 1.49, mean duration of diabetes: 8.4 +/- 5.2 years. The proportion of patients with ACR 3 mg/mmol and or = 3 mg/mmol was 65.5 percent and 34.5 percent, respectively, 32.8 percent of patients had urine microalbumin. The sensitivity, specificity and accuracy of the semi-quantitative method was 86.7 percent, 80 percent, 83.3 percent, respectively (p 0.001). ROC diagram suggested that the urine ACR was good parameter in diagnosis of renal diabetic complications (area under the curve was 0.815). There was a strong correlation between the concentration of albumin, creatinine concentration, random urine ACR measured on 2 machines UX2000 and Cobas 6000. Conclusion: Random urine ACR determined by semi-quantitative method was reliable test in the diagnosis of renal diabetic complications.

TTKHCNQG, CVv 46