Soil erosion is the main reason of the soil degradation in the mountain and plateau areas in Vietnam. Soil in Tay Nguyen are losing productivity because erosion. This research was used the Universal Soil Loss Equation (USLE) was established by Wischmeier W.H and Smith D.D., together with Geographical Information System (GIS) tool and soil profile in the fields to establish soil erosion potential map and assess soil loss level in each part of Tay Nguyen. The soil erosion level I was occupied 79,10 percent of the total iirea; the soil erosion level II was hold 16,57 percent of the total area; the soil erosion level III was occupied 2,78 percent of the total area; and each or the level IV and V weren't over 1 percent of the total area. In Tay Nguyen can be applied many methods for protecting soil avoid erosion. That are using land cover (including vegetation and cultivate method) as forest reproduction with native plants; using agro-forestry models in the slope land; planting the suitable vegetation or crop; and ensuring that slope land has dense vegetation cover during the rain reason.