Using sets of cell panel which are made in NIHBT to screen and identify irregular antibodies for patients and blood donors in some transfusion centres and hospitals and assess quality of reagents is necessary. Objectives: "Study on results of blood donor's irregular antibodies screening and identifying and patients' irregular antibodies screening and identifying in some transfusion centres and hospitals by using sets of screening eel panel and identifying cell panel which are made in NIHBT". Materials: NIHBT: 1,068 patients and 128,600 blood donors; Thanh Hoa hematology and blood transfusion centre: 152 patients and 150 blood donors; Thai Nguyen hematology and blood transfusion centre: 100 patients and 120 blood donors; Cho Ray hospital: 100 patients and 400 blood donors; Ho Chi Minh hematology and blood transfusion hospital: 50 patients and 450 blood donors. Methods: crosssectional survey. Using sets of screening eel panel and identifying cell panel which are made in NIHBT test for patients and donors. Results: Ratio of patients' irregular antibodies in NIHBT was 5.8 percent, donors' was 0.004 percent. Anti Mia made up highest ratio (37.1 percent), following anti-E (20.97 percent) and anti-c (11.29 percent). Ratio of patients' irregular antibodies in Thanh Hoa, Thai Nguyen hematology and blood transfusion centre, Cho Ray hospital and Ho Chi Minh hematology and blood transfusion hospital were 3.3 percent; 3.22 percent; 29 percent and 6 percent respectively; the investigation didn't meet any donors who had irregular antibodies. Anti-Jkb made up highest ratio in Cho Ray hospital (33.33 percent). Anti-E made up 100 percent in Ho Chi Minh hematology and blood transfusion hospital. The more blood units the patients were transfused the more irregular antibodies the patients had. Conclusions: Ratio of patients' irregular antibodies in NIHBT, Thanh Hoa, Thai Nguyen hematology and blood transfusion centre, Cho Ray hospital and Ho Chi Minh hematology and blood transfusion hospital were 5.8 percent; 3.3 percent; 3.22 percent; 29 percent and 6 percent respectively. The more blood units the patients were transfused the more irregular antibodies the patients had. In NIHBT anti Mia made up highest ratio (37.1 percent), following anti-E (20,97 percent) and anti-c (11.29 percent). Anti-Jkb made up highest ratio in Cho Ray hospital (33.33 percent). Anti-E made up 100 percent in Ho Chi Minh hematology and blood transfusion hospital.
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