Thông tin nhà nghiên cứu KH&CN

Tối ưu hóa quy trình điều chế cao phun sấy bưởi non

Xây dựng quy trình định lượng đồng thời naringin và hai chất bảo quản trong cao bưởi non

Xây dựng quy trình định lượng đồng thời naringin và hesperidin trong quả bưởi non bằng phương pháp sắc ký lỏng đầu dò PDA

Xây dựng quy trình định lượng đồng thời naringin và hesperidin trong quả bưởi non bằng phương pháp điện di mao quản đầu dò PDA

Mức giá sẵn lòng chi trả dịch vụ chăm sóc sức khỏe tại nhà của người bệnh ở Bệnh viện Lê Văn Thịnh, thành phố Thủ Đức, năm 2021-2022

Liệu pháp kháng thể đơn dòng kháng virus trong điều trị Covid-19

Liệu pháp miễn dịch interleukin-2 trong điều trị ung thư

SARS-CoV-2 gây bệnh viêm đường hô hấp cấp: cấu trúc và các thuốc điều trị tiềm năng

Tổng hợp 8-cloro-1,3,7-trimethyl-3,7-dihydro-1H-purin-2,6-dion (8-clorocafein) tạp E của dimenhydrinat dùng làm chất đối chiếu

Tổng hợp tạp chuẩn D của amlodipin từ amlodipin besylat

Identification of efflux pump inhibitors for Pseudomonas aeruginosa MexAB-OprM via ligand-based pharmacophores, 2D-QSAR, molecular docking and molecular dynamics approaches.

Recent Advances in Computational Modeling of Multi-targeting Inhibitors as Anti-Alzheimer Agents

Discovery of AcrAB-TolC pump inhibitors: Virtual screening and molecular dynamics simulation approach

Discovery of a novel AcrAB-TolC pump inhibitor using the multistep virtual screening, synthesis and biological evaluation of asymmetric imidazole-4, 5-dicarboxamide derivatives

Towards Unveiling Putative Binding Sites of Interleukin-33: Insights from Mixed-Solvent Molecular Dynamics Simulations of the Interleukin-1 Family.

Nghiên cứu tối ưu hóa quy trình điều chế doxophyllin từ dyphyllin

Pore engineering of biomolecule-based metal–organic framework nanocarriers for improving loading and release of paclitaxel. New Journal of Chemistry, 2022, 46 (14), 6630-6635, https://doi.org/10.1039/D2NJ00416J

Zeolitic imidazolate frameworks as an efficient platform for potential curcumin-based on/off fluorescent chemosensor. Microporous and Mesoporous Materials, Volume 327, November 2021, 111445

Synthesis and establishement of Amlodipine impurity G reference standard, Journal of Applied Pharmaceutical Science Vol 7(10), pp 105-110, 10/2017.

Antimicrobial and Efflux pump Inhibitory Activity of Carvocacetones from Sphaerantus africanus Against Mycobacteria, Antibiotics 2020, 9(7), 390 (http://www.mdpi.com/2079-6382/9/7/390)

Peramivir binding affinity with influenza A neuraminidase and research on its mutations using an induced-fit docking approach. SAR and QSAR in Environmental Research, 2019, Vol. 30, issue 12, 899–917. (10.1080/1062936X.2019.1679248)

Design of Curcumin and Flavonoid Derivatives with Acetylcholinesterase and Beta-Secretase Inhibitory Activities Using in Silico Approaches. Molecules 2020, 25(16), 3644. (10.3390/molecules25163644)

Synthesis, In Silico and In Vitro Evaluation for Acetylcholinesterase and BACE-1 Inhibitory Activity of Some N-Substituted-4-Phenothiazine-Chalcones. Molecules 2020, 25(17), 3916. ( 10.3390/molecules25173916)

Synthesis, In Silico and In Vitro Evaluation of Some Flavone Derivatives for Acetylcholinesterase and BACE-1 Inhibitory Activity. Molecules 2020, 25(18), 4064. (10.3390/molecules25184064. Synthesis, In Silico and In Vitro Evaluation of Some Flavone Derivatives for Acetylcholinesterase and BACE-1 Inhibitory Activity. Molecules 2020, 25(18), 4064. (10.3390/molecules25184064)

Structure-based discovery of interleukin-33 inhibitors: a pharmacophore modeling, molecular docking, and molecular dynamics simulations approach. SAR and QSAR in Environmental Research, 2020, Vol. 31, issue 12, 883-904 (10.1080/1062936X.2020.1837239)

Prediction model of human ABCC2/MRP2 efflux pump inhibitors: a QSAR study. Molecular Diversity, 2021, Vol. 25, issue 2, 741-751 (10.1007/s11030-020-10047-9)

Structure-based discovery of ABCG2 inhibitors: a homology protein-based pharmacophore modeling and molecular docking approach. Molecules 2021, 26(11), 3115 (10.3390/molecules26113115).

Discovery of small molecular inhibitors for interleukin-33/ST2 protein–protein interaction: a virtual screening, molecular dynamics simulations and binding free energy. Molecular Diversity, 2022, 26(5), 2659–2678 (10.1007/s11030-021-10359-4)

Chalcone derivatives as potential inhibitors of P-glycoprotein and NorA: an in silico and in vitro study. BioMed Research International, 2022, 9982453. (10.1155/2022/9982453)

Identification of potential interleukin-8 inhibitors acting on the interactive site between chemokine and CXCR2 receptor: a computational approach. Plos One, 2022, 17(2), e0264385 (10.1371/journal.pone.0264385)

Structure-Based 3D-Pharmacophore Modeling to Discover Novel Interleukin 6 Inhibitors: An In silico Screening, Molecular Dynamics Simulations and Binding Free Energy Calculations. Plos One, 2022, 17(4), e0266632. (10.1371/journal.pone.0266632)

Exploration of chalcones as 3-chymotrypsin like protease (3CLpro) inhibitors of SARS-CoV-2 using computational approaches. Structural Chemistry, 2022, 33(5), 1707–1725 (10.1007/s11224-022-02000-3)

Identification of Diosmin and Flavin adenine dinucleotide as repurposing treatments for monkeypox virus: a computational study. International Journal of Molecular Sciences, 2022, 23(19), 11570 (10.3390/ijms231911570)

LY3041658/ Interleukin-8 complex structure as targets for IL-8 small molecule inhibitors discovery using a combination of in silico methods. SAR and QSAR in Environmental Research, 2022, Vol. 33, issue 10, 753-778 (10.1080/1062936X.2022.2132536)

Identification of small molecules as potential inhibitors of interleukin 6: a multi-computational investigations. Molecular Diversity, 2022, on line first. (10.1007/s11030-022-10558-7)

Discovery Of AcrAB-TolC Pump Inhibitors: Virtual screening and Molecular Dynamic Simulation Approach. Journal of Biomolecular Structure and Dynamics, 2023, (10.1080/07391102.2023.2175381).

Targeting Olokizumab-Interleukin 6 interaction interface to discover novel IL-6 inhibitors. Journal of Biomolecular Structure and Dynamics, 2023, (10.1080/07391102.2023.2193990).

In silico approach to identify novel allosteric intracellular antagonist for blocking the interleukin-8/ CXCR2 receptor signaling pathway. Journal of Biomolecular Structure and Dynamics, 2023, (10.1080/07391102.2023.2171136 )

Machine learning-, rule- and pharmacophore-based classification on the inhibition of P-glycoprotein and NorA (ID: 1233137 DOI:10.1080/1062936X.2016.1233137)

“Computational Approaches for the Discovery of Novel Hepatitis C Virus NS3/4A and NS5B Inhibitors” in "Oncology: Breakthroughs in Research and Practice". ISBN13: 9781522505495. IGI Global. 2017, pages 482-518. http://dx.doi.org/10.4018/978-1-5225-0549-5.ch017

Hóa Dược I - Chủ biên: Lê Minh Trí - Huỳnh Thị Ngọc Phương, Nhà xuất bản Giáo Dục, 2010

Trieu-Du Ngo, Thanh-Dao Tran, Minh-Tri Le, Khac-Minh Thai. Computational predictive models for P-glycoprotein inhibition of in-house chalcone derivatives and drug-bank compounds. PO-PC-32. Conference Proceedings of The 1st International Conference on Pharmacy Education and Research Network of ASEAN, ISBN 978-616-279-768-2, 2015, 453-457

Quoc-Hiep Dong, Minh-Tri Le, Thi-Thu-Ha Nguyen, Khac-Minh Thai. Modeling and virtual screening of P1-P3 macrocyclic analogs as Ns3/4a serine protease inhibitors. P0-PC-06. Conference Proceedings of The 1st International Conference on Pharmacy Education and Research Network of ASEAN, ISBN 978-616-279-768-2, 2015, 387-392

Trieu-Du Ngo, Thanh-Dao Tran, Minh-Tri Le, Khac-Minh Thai. Machine learning-, rule- and pharmacophore-based classification on the inhibition of two efflux pumps P-glycoprotein and NorA. OR-PC-03. Conference Proceedings of The 1st International Conference on Pharmacy Education and Research Network of ASEAN, ISBN 978-616-279-768-2, 2015, 352-356

Synthesis of Novel Chalcones as Acetylcholinesterase Inhibitors. Applied Sciences. 2016, Vol. 6, Issue 7, 198. http://www.mdpi.com/2076-3417/6/7/198

Computational predictive models for P-glycoprotein inhibition of in-house chalcone derivatives and drug-bank compounds. Molecular Diversity, 2016, Vol. 20, Issue 4, pp xx-xx in press. http://dx.doi.org/10.1007/s11030-016-9688-5

Synthesis and Selective Cytotoxic Activities on Rhabdomyosarcoma and Noncancerous Cells of Some Heterocyclic Chalcones. Molecules 2016, 21(3), 329 (http://dx.doi.org/10.3390/molecules21030329)

Computational assay of Zanamivir binding affinity with original and mutant influenza neuraminidase 9 using molecular docking. Journal of Theoretical Biology, 2015, Vol. 385, 31-39. http://dx.doi.org/10.1016/j.jtbi.2015.08.019

Hua Ngoc Minh Tuyen, Le Duy Phong, Le Minh Tri, Thai Khac Minh. 3D-pharmacophore modelling on retinoic acid receptor. Proceedings of The Eighth Indochina Conference on Pharmaceutical Sciences, ISBN 604660159-2, 2013, 497-502

Thái Khắc Minh, Lê Minh Trí, Nguyễn Đắc Chí, Nguyễn Thị Xuân, Đoàn Cao Sơn. Nghiên cứu xây dựng mô hình 3D QSAR trên hoạt tính ức chế P. falciparum enoyl acyl reductase (PfENR) của các dẫn chất Triclosan. Tạp chí Hóa Học, 2012, 50(5A), 238-241

Thái Khắc Minh, Nguyễn Hữu Nhân Tâm, Nguyễn Thị Thu Hà, Lê Minh Trí, Đoàn Cao Sơn. Mô hình docking của các dẫn chất hydroxamat và mercaptoacetamid trên histon deacetylase 8 - HDAC8. Y học Thành Phố Hồ Chí Minh, 2013, Tập 17, phụ bản 1, trang 9-15

“Computational Approaches for the Discovery of Novel Hepatitis C Virus NS3/4A and NS5B Inhibitors” in "Quantitative Structure-Activity Relationships in Drug Design, Predictive Toxicology, and Risk Assessment" Ed. Kunal Roy. ISBN13: 9781466681361. IGI Global. 2015, pages 318-353. Link (http://dx.doi.org/10.4018/978-1-4666-8136-1.ch009)

Virtual Screening for Novel Staphylococcus aureus NorA Efflux Pump Inhibitors from Natural Products. Medicinal Chemistry, 2015, Vol. 11, issue 2, 135-155. (http://dx.doi.org/10.2174/1573406410666140902110903)

Preparation of microcrystalline cellulose from the bagasse. Proceedings of the 4th Indochina Conference on Pharmaceutical Science “Pharmacy in Cooperation for Development and Integration” organized by School of Pharmacy, University of Medicine and Pharmacy at HCM City, Nov. 10-13, 2005, HCM City, Vietnam

Anti-inflammatory chrysin derivatives – molecular modeling study on cyclooxygenase-2 active site. Proceedings of the Fourth Indochina Conference on Pharmaceutical Science, 2005, Vol. 2, pp 478-483.

Synthesis and biological evaluation of halogen substituted 1,4-naphthoquinones as potent antifungal agents

Novel halogen substituted 1,4-naphthoquinones: synthesis and biological evaluation of as potent antifungal agents. Proceedings of the 6th Indochina Conference on Pharmaceutical Science, Dec. 15-18, 2009, Hue, Vietnam

Pharmacophore modeling for antitargets. Current Topics in Medicinal Chemistry, 2013, Vol.13, issue 9, pp 1002-1014 (http://eurekaselect.com/110539/article ) http://www.ncbi.nlm.nih.gov/pubmed/23651480

Nghiên cứu quy trình công nghệ tổng hợp ba dẫn xuất từ theophyllin

Thiết kế và tổng hợp các dẫn chất flavonoid và curcumin có hoạt tính ức chế sự thành lập và kết tập β-amyloid

Hoàn thiện quy trình công nghệ sản xuất 3 nguyên liệu dạng gel ướt magie hydroxyd nhôm hydroxyd nhôm phosphat và sản xuất thuốc điều trị đau dạ dày

Nghiên cứu sản xuất sản phẩm bảo vệ sức khỏe từ bào tử linh chi đã được phá vách

Sản xuất viên nang giàu flavonoid hỗ trợ điều trị rối loạn lipid và giảm béo phì từ nguồn bưởi non dư phẩm

Thiết kế và tổng hợp các dẫn chất flavonoid và curcumin có hoạt tính ức chế sự thành lập và kết tập β-amyloid

Nghiên cứu bào chế thuốc tiêm paclitaxel ở qui mô pilot, mã số KC.10.24/11-15

Ảnh hưởng của thức ăn giàu lipid và nước hoa quả (cam) lên sự hấp thu của cyclosporin A trên người tình nguyện Việt Nam

Nghiên cứu sự hấp thu qua da của artemisinin trên chuột nhắt trắng nhiễm Plasmodium berghei