



- Công bố khoa học và công nghệ Việt Nam
76
Dược liệu học; Cây thuốc; Con thuốc; Thuốc Nam, thuốc dân tộc
Nguyễn Thị Bích Hằng, Đặng Minh Nhật, Đoạn Chí Cường(1), Bùi Đức Thắng
Khảo sát hoạt tính prebiotic của polysaccharide chiết xuất từ sợi nấm đông trùng hạ thảo (Cordyceps militaris)
Prebiotic properties of polysaccharides isolated from Cordyceps militaris mycelia
Tạp chí Công Thương
2023
4
413-420
0866-7756
Polysaccharides (PS) are the major bioactive ingredients in Cordyceps militaris (C.militaris). This study evaluated the prebiotics activity of c.militaris in liquid culture. Findings indicated that PS extracted from this mycelium could promote the growth of beneficial microorganisms in the intestine, Lactobacillus plantarum (L.plantarum). The extract from this bacterial culture medium is able to inhibit the growth of Escherichia coll (E.coli) and Staphylococcus aureus (S.aureus) with inhibition zones of 19.33 ± 0.577 mm, and 21.67 + 1.443 mm, respectively. The solution culture of L.plantarum supplemented with c.militaris’s mycelium reduces the pH of the medium and produces short-chain fatty acids (SCFAs) with acetic, butyric, and propionic acid contents of 11626 mg/L, 8047.5 mg/L and 334.78 mg/L, respectively. The results show the potential to use c.militaris’s mycelium as a raw material for prebiotics production to replace other commercial prebiotics on the market.
TTKHCNQG, CVv 146